Recombinant humaan FGG-eiwit

FGG, also Known as Fibrinogen gamma chain isoform gamma-A. FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, FGG is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Recombinant human FGG, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Fibrinogen gamma chain isoform gamma-A, Fibrinogen gamma chain

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

48.9 kDa (434aa) confirmed by MALDI-TOF

FGG, ATGP2953-10 µg, ATGP2953-20 µg, ATGP2953-50 µg, ATGP2953-100 µg, ATGP2953-250 µg, ATGP2953-500 µg, ATGP2953-1 mg, ATGP2953-10, ATGP2953-20, ATGP2953-50, ATGP2953-100, ATGP2953-250, ATGP2953-500, ATGP2953-1

Abaeva AA., et al. (2013) J. Biol. Chem. 288 (41), 29621-29632

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Cardiovascular

NP_000500

P02679

Human

YVATRDN CCILDERFGS YCPTTCGIAD FLSTYQTKVD KDLQSLEDIL HQVENKTSEV KQLIKAIQLT YNPDESSKPN MIDAATLKSR KMLEEIMKYE ASILTHDSSI RYLQEIYNSN NQKIVNLKEK VAQLEAQCQE PCKDTVQIHD ITGKDCQDIA NKGAKQSGLY FIKPLKANQQ FLVYCEIDGS GNGWTVFQKR LDGSVDFKKN WIQYKEGFGH LSPTGTTEFW LGNEKIHLIS TQSAIPYALR VELEDWNGRT STADYAMFKV GPEADKYRLT YAYFAGGDAG DAFDGFDFGD DPSDKFFTSH NGMQFSTWDN DNDKFEGNCA EQDGSGWWMN KCHAGHLNGV YYQGGTYSKA STPNGYDNGI IWATWKTRWY SMKKTTMKII PFNRLTIGEG QQHHLGGAKQ AGDV