Recombinant humaan FHL2-eiwit

FHL2 is a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human FHL2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Four and a half LIM domains 2, AAG11, DRAL, FHL-2, SLIM-3, SLIM3

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

34.6 kDa (302aa)

FHL2, Four and a half LIM domains 2, AAG11, DRAL, FHL-2, SLIM-3, SLIM3, ATGP2857-10 µg, ATGP2857-20 µg, ATGP2857-50 µg, ATGP2857-100 µg, ATGP2857-250 µg, ATGP2857-500 µg, ATGP2857-1 mg, ATGP2857-10, ATGP2857-20, ATGP2857-50, ATGP2857-100, ATGP2857-250, ATGP2857-500, ATGP2857-1

Verset, L., et al. (2013) Br. J. Cancer 109 (1), 114-120; ; Han, W., et al. (2013) J. Clin. Invest. 123 (5), 2103-2118

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Epigenomics (Transcription & Translation)

NP_001034581

Q14192

Human

MTERFDC HHCNESLFGK KYILREESPY CVVCFETLFA NTCEECGKPI GCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL LCTDCYSNEY SSKCQECKKT IMPGTRKMEY KGSSWHETCF ICHRCQQPIG TKSFIPKDNQ NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTARDDFA YCLNCFCDLY AKKCAGCTNP ISGLGGTKYI SFEERQWHND CFNCKKCSLS LVGRGFLTER DDILCPDCGK DI