Recombinant humaan FIBP-eiwit

Acidic fibroblast growth factor intracellular-binding protein isoform a, also known as FIBP, is a member of Fibroblast growth factors (FGFs) represent a family. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer progression. FIBP is a 364 amino acid protein that binds to internalized FGF-1 and is thought to be involved in mitogenic function of FGF-1. FIBP localizes to the nucleus and is highly expressed in heart, skeletal muscle and pancreas and at lower levels in brain, placenta, liver and kidney. Recombinant human FIBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Acidic fibroblast growth factor intracellular-binding protein, FGFIBP, FIBP-1, FIBP1, aFGF intracellular-binding protein

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

44.3 kDa (387aa) confirmed by MALDI-TOF

FIBP, Acidic fibroblast growth factor intracellular-binding protein, FGFIBP, FIBP-1, FIBP1, aFGF intracellular-binding protein, ATGP2145-10 µg, ATGP2145-20 µg, ATGP2145-50 µg, ATGP2145-100 µg, ATGP2145-250 µg, ATGP2145-500 µg, ATGP2145-1 mg, ATGP2145-10, ATGP2145-20, ATGP2145-50, ATGP2145-100, ATGP2145-250, ATGP2145-500, ATGP2145-1

Kolpakova E., et al. (1998) Biocham J. 336:213-222; ; Volkin D B., et al. (1996) Biotechnol. 9:181-217.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_942600

O43427

Human

MGSSHHHHHH SSGLVPRGSH MGSMTSELDI FVGNTTLIDE DVYRLWLDGY SVTDAVALRV RSGILEQTGA TAAVLQSDTM DHYRTFHMLE RLLHAPPKLL HQLIFQIPPS RQALLIERYY AFDEAFVREV LGKKLSKGTK KDLDDISTKT GITLKSCRRQ FDNFKRVFKV VEEMRGSLVD NIQQHFLLSD RLARDYAAIV FFANNRFETG KKKLQYLSFG DFAFCAELMI QNWTLGAVGE APTDPDSQMD DMDMDLDKEF LQDLKELKVL VADKDLLDLH KSLVCTALRG KLGVFSEMEA NFKNLSRGLV NVAAKLTHNK DVRDLFVDLV EKFVEPCRSD HWPLSDVRFF LNQYSASVHS LDGFRHQALW DRYMGTLRGC LLRLYHD