Recombinant humaan FOLR1-eiwit

FOLR1, as known as folate receptor alpha, is a member of the folate receptor family. This protein meditates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide ad methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. Also, mature form is an N-glycosylated protein that is anchored to the cell surface by a GPI linkages. Recombinant human FOLR1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Folate receptor alpha, FOLR1, FBP, FOLR

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

25.6 kDa (218aa)

FOLR1, Folate receptor alpha, FOLR1, FBP, FOLR, ATGP3518-10 µg, ATGP3518-20 µg, ATGP3518-50 µg, ATGP3518-100 µg, ATGP3518-250 µg, ATGP3518-500 µg, ATGP3518-1 mg, ATGP3518-10, ATGP3518-20, ATGP3518-50, ATGP3518-100, ATGP3518-250, ATGP3518-500, ATGP3518-1

Hansen MJ., et al, (2015) Inflamm. Res. 64:697-706.; ; Ab O., et al, (2015) Mol. Cancer Ther. 14:1605-1613.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_000793.1

P15328

Human

Ala

IAWARTE LLNVCMNAKH HKEKPGPEDK LHEQCRPWRK NACCSTNTSQ EAHKDVSYLY RFNWNHCGEM APACKRHFIQ DTCLYECSPN LGPWIQQVDQ SWRKERVLNV PLCKEDCEQW WEDCRTSYTC KSNWHKGWNW TSGFNKCAVG AACQPFHFYF PTPTVLCNEI WTHSYKVSNY SRGSGRCIQM WFDPAQGNPN EEVARFYAAA MS