Recombinant humaan FXYD5/Dysadherine-eiwit

FXYD domain-containing ion transport regulator 5, also known as FXYD5, is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. FXYD5 is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis tissue, and maps to human chromosome 19q13. 2. Recombinant human FXYD5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

FXYD domain-containing ion transport regulator 5, DYSAD, HSPC113, IWu1, KCT1, OIT2, PRO6241, RIC

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by BCA assay)

> 95% by SDS-PAGE

16.1 kDa (147aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

FXYD5, Dysadherin, FXYD domain-containing ion transport regulator 5, DYSAD, HSPC113, IWu1, KCT1, OIT2, PRO6241, RIC, ATGP1968-10 µg, ATGP1968-20 µg, ATGP1968-50 µg, ATGP1968-100 µg, ATGP1968-250 µg, ATGP1968-500 µg, ATGP1968-1 mg, ATGP1968-10, ATGP1968-20, ATGP1968-50, ATGP1968-100, ATGP1968-250, ATGP1968-500, ATGP1968-1

Shimamura T., et al. (2003) J Clin Oncol. 21:659-667; ; Sato H., et al. (2003) Metab. 9: 4407-4412.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Signal Transduction

NP_001158077.1

Q96DB9

Human

QTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR