Recombinant humaan GADD45GIP1-eiwit

GADD45GIP1, also known as CRIF1, is a nuclear protein that plays a role in apoptosis control. This protein is expressed in a variety of tissues, including heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach. It functions as a negative regulator of G1 to S phase cell cycle production, specifically by working with GADD45 proteins to inhibit the activity of cyclin-dependent kinases. Recombinant human GADD45GIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Growth arrest and DNA damage-inducible proteins-interacting protein 1, CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

22.6 kDa (196aa) confirmed by MALDI-TOF

GADD45GIP1, Growth arrest and DNA damage-inducible proteins-interacting protein 1, CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, ATGP1280-10 µg, ATGP1280-20 µg, ATGP1280-50 µg, ATGP1280-100 µg, ATGP1280-250 µg, ATGP1280-500 µg, ATGP1280-1 mg, ATGP1280-10, ATGP1280-20, ATGP1280-50, ATGP1280-100, ATGP1280-250, ATGP1280-500, ATGP1280-1

Chung HK., et al. (2003) J Biol Chem. 278 (30) :28079-88.; ; Park KC., et al. (2005) Mol Endocrinol. 19 (1) :12-24.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 2mM DTT, 0.2M NaCl.

Cancer

NP_443082

Q8TAE8

Human

MGSSHHHHHH SSGLVPRGSH MPRWQLGPRY AAKQFARYGA ASGVVPGSLW PSPEQLRELE AEEREWYPSL ATMQESLRVK QLAEEQKRRE REQHIAECMA KMPQMIVNWQ QQQRENWEKA QADKERRARL QAEAQELLGY QVDPRSARFQ ELLQDLEKKE RKRLKEEKQK RKKEARAAAL AAAVAQDPAA SGAPSS