Recombinant humaan Galectine-2/Lgals2-eiwit

LGALS2, also known as galectin2, is a soluble beta-galactoside binding lectin that modulates cell-to-cell adhesion and cell-to-extracellular matrix interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. This protein induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with possible implications in risk of myocardial infarction. Recombinant human Galectin 2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Galectin2, HL14, Gal-2, Beta-galactoside-binding lectin L-14-II, Lactose-binding lectin 2, S-Lac lectin 2

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

16.8 kDa (152aa) confirmed by MALDI-TOF

Galectin2, ATGP0680-10 µg, ATGP0680-20 µg, ATGP0680-50 µg, ATGP0680-100 µg, ATGP0680-250 µg, ATGP0680-500 µg, ATGP0680-1 mg, ATGP0680-10, ATGP0680-20, ATGP0680-50, ATGP0680-100, ATGP0680-250, ATGP0680-500, ATGP0680-1

Loser K., et al. (2009) J Immunol. 182 (9) :5419-29.; ; Ozaki K., et al. (2009) Nat Genet. 41 (3) :329-33.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol

Apoptosis

NP_006489

P05162

Human

MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG ELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE