Recombinant humaan Galectine-4/LGALS4-eiwit

Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E. coli and purified by using conventional chromatography techniques.

The ED50 range ≤2 µg/mL. Measured by its ability to ability to agglutinate human red blood cells.

Gal-4, Antigen NY-CO-27, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4

E.coli

Human

His-Tag

SDS-PAGE, Bioactivity

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

The ED50 ≤2 µg/mL. Measured by its ability to ability to agglutinate human red blood cells.

38.1 kDa (343aa) confirmed by MALDI-TOF

Galectin4, ATGP0409-10 µg, ATGP0409-20 µg, ATGP0409-50 µg, ATGP0409-100 µg, ATGP0409-250 µg, ATGP0409-500 µg, ATGP0409-1 mg, ATGP0409-10, ATGP0409-20, ATGP0409-50, ATGP0409-100, ATGP0409-250, ATGP0409-500, ATGP0409-1

Huflejt ME., et al. (1997) J Biol Chem. 272 (22) :14294-303. ; ; Huflejt ME., et al. (2004) Glycoconj J. 20 (4) :247-55.;

Campanero-Rhodes M.A et al., Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures. (Biomolecules. 2021) {https://pubmed.ncbi.nlm.nih.gov/33919637/}; ; Fabregat FN et al., Structure of the Lipopolysaccharide from Paenalcaligenes hominis: A Chemical Perspective on Immune Recognition. (JACS Au. 2025) {https://pubmed.ncbi.nlm.nih.gov/33919637/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Adhesion & Movement

NP_006140

P56470

Human

MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI