Recombinant humaan Galectine-7/Lgals7 eiwit

LGALS7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium, LGALS7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant human LGALS7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Galectin7, GAL7, LGALS7A, HKL-14, PI7, p53-induced gene 1 protein, TP53I1, PIG1, LGALS7A

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

17.2 kDa (156aa) confirmed by MALDI-TOF

Galectin7, Galectin7, GAL7, LGALS7A, ATGP0986-10 µg, ATGP0986-20 µg, ATGP0986-50 µg, ATGP0986-100 µg, ATGP0986-250 µg, ATGP0986-500 µg, ATGP0986-1 mg, ATGP0986-10, ATGP0986-20, ATGP0986-50, ATGP0986-100, ATGP0986-250, ATGP0986-500, ATGP0986-1

Magnaldo T., et al. (1995) Dev Biol. 168 (2) :259-71. ; ; Magnaldo T., et al. (1998) Differentiation. 63 (3) :159-68.

Fabregat FN et al., Structure of the Lipopolysaccharide from Paenalcaligenes hominis: A Chemical Perspective on Immune Recognition. (JACS Au. 2025) {https://doi.org/10.1021/jacsau.5c00441}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Cancer

NP_002298

P47929

Human

MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH FNPRLDTSEV VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA VVGDAQYHHF RHRLPLARVR LVEVGGDVQL DSVRIF