Recombinant humaan GDNFR alfa-3/GFRA3-eiwit

GFRA3 is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Recombinant human GFRA3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

GDNF family receptor alpha-3, GFRA3, GDNFR3, GFRalpha3

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

40.7 kDa (366aa)

GFR a3, GDNF family receptor alpha 3, GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GFR-alpha-3, GFRa-3, ATGP2398-10 µg, ATGP2398-20 µg, ATGP2398-50 µg, ATGP2398-100 µg, ATGP2398-250 µg, ATGP2398-500 µg, ATGP2398-1 mg, ATGP2398-10, ATGP2398-20, ATGP2398-50, ATGP2398-100, ATGP2398-250, ATGP2398-500, ATGP2398-1

Baloh R.H., et al. (1998) Neuron. 21:1291-1302; ; Wang X., et al. (2008) Structure. 14:1083-1092;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Neuroscience

NP_001487

O60609

Human

MGSSHHHHHH SSGLVPRGSH MGSDPLPTES RLMNSCLQAR RKCQADPTCS AAYHHLDSCT SSISTPLPSE EPSVPADCLE AAQQLRNSSL IGCMCHRRMK NQVACLDIYW TVHRARSLGN YELDVSPYED TVTSKPWKMN LSKLNMLKPD SDLCLKFAML CTLNDKCDRL RKAYGEACSG PHCQRHVCLR QLLTFFEKAA EPHAQGLLLC PCAPNDRGCG ERRRNTIAPN CALPPVAPNC LELRRLCFSD PLCRSRLVDF QTHCHPMDIL GTCATEQSRC LRAYLGLIGT AMTPNFVSNV NTSVALSCTC RGSGNLQEEC EMLEGFFSHN PCLTEAIAAK MRFHSQLFSQ DWPHPTFAVM AHQNEN