Recombinant humaan Ghereline/Obestatine-eiwit

Ghrelin, also known as Obestatin, is the ligand for growth hormone secretagogue receptor type 1 (GHSR) . It induces the release of growth hormone from the pituitary and involved in growth regulation. This protein has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Ghrelin plays a significant role in neurotrophy, particularly in the hippocampus, and is essential for cognitive adaptation to changing environments and the process of learning. Recombinant Ghrelin protein was expressed in E. coli and purified by using conventional chromatography techniques.

Appetite-regulating hormone, Obestatin, GHRL, MTLRP, Ghrelin-27, Ghrelin-28, M-46 protein, Appetite-regulating hormone Appetite regulating hormone, Ghrelin 27, Ghrelin 28, Ghrelin/obestatin prepropeptide, Motilin related peptide, Growth hormone releasing peptide, Growth hormone secretagogue, M46 protein

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

12.8 kDa (115aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Ghrelin, Obestatin, Appetite-regulating hormone, Obestatin, GHRL, MTLRP, Ghrelin-27, Ghrelin-28, M-46 protein, Appetite-regulating hormone Appetite regulating hormone, Ghrelin 27, Ghrelin 28, Ghrelin/obestatin prepropeptide, Motilin related peptide, Growth hormone releasing peptide, Growth hormone secretagogue, M46 protein, ATGP0411-10 µg, ATGP0411-20 µg, ATGP0411-50 µg, ATGP0411-100 µg, ATGP0411-250 µg, ATGP0411-500 µg, ATGP0411-1 mg, ATGP0411-10, ATGP0411-20, ATGP0411-50, ATGP0411-100, ATGP0411-250, ATGP0411-500, ATGP0411-1

Tschop M, et al. (2000) Nature. 407:908-913.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.2M NaCl, 0.1mM PMSF

Hormones & Cytokines

AAH25791

Q9UBU3

Human

MGSSFLSPEH QRVQQRKESK KPPAKLQPRA LAGWLRPEDG GQAEGAEDEM EVRFNAPFDV GIKLSGVQYQ QHSQALGKFL QDILWEEAKE APADK