Recombinant humaan GIMAP6-eiwit

GIMAP6 is a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. Recombinant human GIMAP6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

GTPase IMAP family member 6 isoform 1, IAN-2, IAN-6, IAN2, IAN6

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

35 kDa (315aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

GIMAP6, GTPase IMAP family member 6 isoform 1, IAN-2, IAN-6, IAN2, IAN6, ATGP2245-10 µg, ATGP2245-20 µg, ATGP2245-50 µg, ATGP2245-100 µg, ATGP2245-250 µg, ATGP2245-500 µg, ATGP2245-1 mg, ATGP2245-10, ATGP2245-20, ATGP2245-50, ATGP2245-100, ATGP2245-250, ATGP2245-500, ATGP2245-1

Krucken J, Schroetel RM, et al. (2004) . Gene. 341:291-304.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT

Cancer

NP_078987

Q6P9H5

Human

MEEEEYE QIPQENPPEE LSQDPVLELS GGLREKEQKT PRRLRLILMG KTGSGKSATG NSILGRDVFE SKLSTRPVTK TSQRRSREWA GKELEVIDTP NILSPQVSPE VADAICQAIV LSAPGPHAVL LVTQLGRFTD EDQQVVRRLQ EVFGVGVLGH TILVFTRKED LAGGSLEDYV RETNNQALAW LDVTLARRHC GFNNRAQGEE QEAQLRELME KVEAIMWENE GDYYSNKAYQ YTQQNFRLKE LQERQVSQGQ GSEDVPGEES WLEGLSQIQK ESEEAHRCLL GKADL