Recombinant humaan GITR Ligand/TNFSF18-eiwit

TNFSF18 also known as tumor necrosis factor ligand superfamily member 18 belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein, fused to His-tag at C-terminus, was expressed in E. coli.

Activation-inducible TNF-related ligand, AITRL, GITRL, Glucocorticoid-induced TNF-related ligand, hGITRL, TL6, TNF superfamily member 18, Tumor necrosis factor (ligand) superfamily member 18

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

15.6 kDa (137aa)

GITR Ligand, TNFSF18, Tumor necrosis factor ligand superfamily member 18, AITRL, GITRL, hGITRL, TL6, ATGP3088-10 µg, ATGP3088-20 µg, ATGP3088-50 µg, ATGP3088-100 µg, ATGP3088-250 µg, ATGP3088-500 µg, ATGP3088-1 mg, ATGP3088-10, ATGP3088-20, ATGP3088-50, ATGP3088-100, ATGP3088-250, ATGP3088-500, ATGP3088-1

Tuyaerts S., et al. (2007) J. Leukoc. Biol. 82:93-105; ; Chattopadhyay K., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Immunology

NP_005083

Q9UNG2

Human