Recombinant humaan GITR/TNFRSF18-eiwit

TNFRSF18, also known as tumor necrosis factor receptor superfamily member 18, belongs to the tumor necrosis factor receptor superfamily. It is receptor for TNFSF18 and seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It is mediated NF-kappa-B activation via the TRAF2/NIK pathway. Recombinant human TNFRSF18, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357, AITR, GITR

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

15.6 kDa (145aa)

GITR, TNFRSF18, TNFRSF18, AITR, CD357, GITR, GITR-D, ATGP3215-10 µg, ATGP3215-20 µg, ATGP3215-50 µg, ATGP3215-100 µg, ATGP3215-250 µg, ATGP3215-500 µg, ATGP3215-1 mg, ATGP3215-10, ATGP3215-20, ATGP3215-50, ATGP3215-100, ATGP3215-250, ATGP3215-500, ATGP3215-1

Gurney A.L., et al. (1999) Curr. Biol. 9:215-218.; ; Kwon B., et al. (1999) J.Biol. Chem. 274:6056-6061.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_004186

Q9Y5U5

Human