Recombinant humaan Glutathion S-transferase mu 1/GSTM1-eiwit

Glutathione S-transferase mu 1 isoform 2, also known as GSTM1, is a glutathione S-transferase that belongs to the mu class. GSTs (glutathione S-transferase) are differentially expressed in lung, liver and kidney tissue and, notably, three isoforms (GSTA1-1, GSTA1-4 and GSTM1) localize to the mitochondria in addition to the cytoplasm. The GSTM1 of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Recombinant human GSTM1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Mu-1, Mu, H-B, GTM1, GTH4, GSTM1b-1b, GSTM1a-1a, GSTM1-1, GST1, Glutathione S-transferase mu 1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

23.6 kDa (203aa)

MU-1, MU1, MU, H-B, GTM1, GTM 1, GTH4, GTH 4, GSTM1b-1b, GSTM1b 1b, GSTM1a-1a, GSTM1a 1a, GSTM1-1, GSTM1 1, GSTM1, GSTM 1, GST1, GST 1, Glutathione S-transferase Mu 1 isoform 1, Glutathione S-transferase Mu 1, ATGP2611-10 µg, ATGP2611-20 µg, ATGP2611-50 µg, ATGP2611-100 µg, ATGP2611-250 µg, ATGP2611-500 µg, ATGP2611-1 mg, ATGP2611-010, ATGP2611-020, ATGP2611-050, ATGP2611-100, ATGP2611-250, ATGP2611-500, ATGP2611-01M

Bartley P A., et al. (2003) Oncogene. 22:7570-7575.; ; Moretti M., et al. (2007) BMC Public Health. 7:270.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Metabolism

NP_666533

P09488

Human

MGSSHHHHHH SSGLVPRGSH RSMPMILGYW DIRGLAHAIR LLLEYTDSSY EEKKYTMGDA PDYDRSQWLN EKFKLGLDFP NLPYLIDGAH KITQSNAILC YIARKHNLCG ETEEEKIRVD ILENQTMDNH MQLGMICYNP EFEKLKPKYL EELPEKLKLY SEFLGKRPWF AGNKGLEKIS AYMKSSRFLP RPVFSKMAVW GNK