Recombinant humaan Glutathion S-transferase omega 2/GSTO2-eiwit

Glutathione S-transferase omega 2, also known as GSTO2, belongs to the GST superfamily and may be involved in catalyzing the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. GSTO2 is related to GSTO1 and is expressed in a variety of tissues throughout the body where it functions to catalyze the conversion of RX and glutathione to HX and R-S-glutathione. Recombinant human GSTO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Glutathione S-transferase omega 2, bA127L20.1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

30.6 kDa (266aa) confirmed by MALDI-TOF

GSTO2, Glutathione S-transferase omega 2, bA127L20.1, ATGP1515-10 µg, ATGP1515-20 µg, ATGP1515-50 µg, ATGP1515-100 µg, ATGP1515-250 µg, ATGP1515-500 µg, ATGP1515-1 mg, ATGP1515-10, ATGP1515-20, ATGP1515-50, ATGP1515-100, ATGP1515-250, ATGP1515-500, ATGP1515-1

Chariyalertsak S., et al. (2009) Tumori. 95:739-743.; ; Andonova I E., et al. (2010) Treat. 121: 497-52.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 1mM DTT, 40% glycerol

Metabolism

NP_899062

Q9H4Y5

Human

MGSSHHHHHH SSGLVPRGSH MGSMSGDATR TLGKGSQPPG PVPEGLIRIY SMRFCPYSHR TRLVLKAKDI RHEVVNINLR NKPEWYYTKH PFGHIPVLET SQCQLIYESV IACEYLDDAY PGRKLFPYDP YERARQKMLL ELFCKVPHLT KECLVALRCG RECTNLKAAL RQEFSNLEEI LEYQNTTFFG GTCISMIDYL LWPWFERLDV YGILDCVSHT PALRLWISAM KWDPTVCALL MDKSIFQGFL NLYFQNNPNA FDFGLC