Recombinant humaan Glutathion S-transferase thèta 2/GSTT2-eiwit

Glutathione S-transferase theta 2, also known as GSTT2, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries. Recombinant human GSTT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Glutathione S-transferase theta 2, GSTT2B

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

29.6 kDa (264aa) confirmed by MALDI-TOF

GSTT2, Glutathione S-transferase theta 2, GSTT2B, ATGP1464-10 µg, ATGP1464-20 µg, ATGP1464-50 µg, ATGP1464-100 µg, ATGP1464-250 µg, ATGP1464-500 µg, ATGP1464-1 mg, ATGP1464-10, ATGP1464-20, ATGP1464-50, ATGP1464-100, ATGP1464-250, ATGP1464-500, ATGP1464-1

Tan KL., et al. (1995) Genomics. 25 (2) :381-7.; ; Hussey AJ., et al. (1992) Biochem J. 286:929-35.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT

Metabolism

NP_000845

P0CG29

Human

MGLELFLDLV SQPSRAVYIF AKKNGIPLEL RTVDLVKGQH KSKEFLQINS LGKLPTLKDG DFILTESSAI LIYLSCKYQT PDHWYPSDLQ ARARVHEYLG WHADCIRGTF GIPLWVQVLG PLIGVQVPEE KVERNRTAMD QALQWLEDKF LGDRPFLAGQ QVTLADLMAL EELMQPVALG YELFEGRPRL AAWRGRVEAF LGAELCQEAH SIILSILEQA AKKTLPTPSP EAYQAMLLRI ARIP