Recombinant humaan Glutathion S-transferase zeta 1/GSTZ1-eiwit

GSTZ1, also known as maleylacetoacetate isomerase, is an enzyme that belongs to glutathione S-transferase (GSTs) super-family. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur) . The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. It also plays a significant role in the catabolism of phenylalanine and tyrosine. Recombinant GSTZ1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Glutathione S-transferase zeta 1, GSTZ1-1, MAAI, MAI, Glutathione S-transferase zeta 1 EC 2.5.1.18, EC 5.2.1.2

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

26.2 kDa (236aa) confirmed by MALDI-TOF

MAI, MAAI, GSTZ1-1, GSTZ1, Glutathione S-Transferase Zeta-1, Glutathione S-transferase zeta1, Glutathione S-transferase zeta 1 EC 2.5.1.18, Glutathione S-transferase zeta 1, Glutathione S transferase zeta1, Glutathione S transferase zeta 1 EC 2.5.1.18, Glutathione S transferase zeta 1, EC 5.2.1.2, GSTZ1 1, ATGP0491-10 µg, ATGP0491-20 µg, ATGP0491-50 µg, ATGP0491-100 µg, ATGP0491-250 µg, ATGP0491-500 µg, ATGP0491-1 mg, ATGP0491-010, ATGP0491-020, ATGP0491-050, ATGP0491-100, ATGP0491-250, ATGP0491-500, ATGP0491-01M

Board PG, et al. (1997) Biochem J. 328:929-35.; ; Fernandez-Canon JM., et al. (1998) J Biol Chem. 273 (1) :329-37;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Metabolism

AAC33591

O43708

Human

MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA