Recombinant humaan GM-CSF R alfa-eiwit

CSF2RA is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. This protein is a member of the cytokine family of receptors. It is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. Recombinant human CSF2RA protein, fused to His-tag at N-terminus, was expressed in E. coli.

Colony stimulating factor 2 receptor alpha low-affinity, Colony stimulating factor 2 receptor, alpha, low-affinity, CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

37.2 kDa (324aa)

GM-CSF R a, Colony stimulating factor 2 receptor alpha low-affinity, Colony stimulating factor 2 receptor, alpha, low-affinity, CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, ATGP2363-10 µg, ATGP2363-20 µg, ATGP2363-50 µg, ATGP2363-100 µg, ATGP2363-250 µg, ATGP2363-500 µg, ATGP2363-1 mg, ATGP2363-10, ATGP2363-20, ATGP2363-50, ATGP2363-100, ATGP2363-250, ATGP2363-500, ATGP2363-1

Hansen G., et al. (2008) Cell. 134:496-507; ; Suzuki T., et al. (2008) J. Exp. Med. 205:2703-2710

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Stem Cell

NP_001155003

P15509

Human

MGSSHHHHHH SSGLVPRGSH MGSLIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDG