Recombinant humaan GMPR-eiwit

GMPR, also known as guanosine monophosphate reductase, catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Recombinant human GMPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Guanosine monophosphate reductase, GMPR1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.5 kDa (365aa) confirmed by MALDI-TOF

GMPR, Guanosine monophosphate reductase, GMPR1, ATGP1410-10 µg, ATGP1410-20 µg, ATGP1410-50 µg, ATGP1410-100 µg, ATGP1410-250 µg, ATGP1410-500 µg, ATGP1410-1 mg, ATGP1410-10, ATGP1410-20, ATGP1410-50, ATGP1410-100, ATGP1410-250, ATGP1410-500, ATGP1410-1

Yoshida A., et al. (1990) Cell. 62:11-12; ; Kanno H., et al. (1989) Cell. 58:595-606

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT

Redox Proteins

AAH08281

P36959

Human

MGSSHHHHHH SSGLVPRGSH MPRIDADLKL DFKDVLLRPK RSSLKSRAEV DLERTFTFRN SKQTYSGIPI IVANMDTVGT FEMAAVMSQH SMFTAIHKHY SLDDWKLFAT NHPECLQNVA VSSGSGQNDL EKMTSILEAV PQVKFICLDV ANGYSEHFVE FVKLVRAKFP EHTIMAGNVV TGEMVEELIL SGADIIKVGV GPGSVCTTRT KTGVGYPQLS AVIECADSAH GLKGHIISDG GCTCPGDVAK AFGAGADFVM LGGMFSGHTE CAGEVIERNG RKLKLFYGMS SDTAMNKHAG GVAEYRASEG KTVEVPYKGD VENTILDILG GLRSTCTYVG AAKLKELSRR ATFIRVTQQH NTVFS