Recombinant humaan GMPR2-eiwit

Guanosine monophosphate reductase 2, also known as GMPR2, is the only known metabolic step by which guanine nucleotides can be converted to the pivotal precursor of both adenine and guanine nucleotides. GMPR2 catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP, and plays a critical role in re-utilization of free intracellular bases and purine nucleosides. Recombinant human GMPR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Guanosine monophosphate reductase 2, GMP reductase 2, Guanosine 5'-monophosphate oxidoreductase 2

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

40 kDa (368aa) confirmed by MALDI-TOF

GMPR2, Guanosine monophosphate reductase 2, GMP reductase 2, Guanosine 5'-monophosphate oxidoreductase 2, ATGP0704-10 µg, ATGP0704-20 µg, ATGP0704-50 µg, ATGP0704-100 µg, ATGP0704-250 µg, ATGP0704-500 µg, ATGP0704-1 mg, ATGP0704-10, ATGP0704-20, ATGP0704-50, ATGP0704-100, ATGP0704-250, ATGP0704-500, ATGP0704-1

Li J., et al. (2006) J Mol Biol. 355 (5) :980-8.; ; Denq Y., et al. (2002) Int J Biochem Cell Biol. 34 (9) :1035-50.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Enzymes & Proteases

NP_001002002

Q9P2T1

Human

MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC