Recombinant humaan GP9-eiwit

GP9 is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. Recombinant human GP9 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Platelet glycoprotein IX, CD42a, GPIX

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

16.8 kDa (154aa)

GP9, Platelet glycoprotein IX, CD42a, GPIX, ATGP1919-10 µg, ATGP1919-20 µg, ATGP1919-50 µg, ATGP1919-100 µg, ATGP1919-250 µg, ATGP1919-500 µg, ATGP1919-1 mg, ATGP1919-10, ATGP1919-20, ATGP1919-50, ATGP1919-100, ATGP1919-250, ATGP1919-500, ATGP1919-1

McEwan, P.A., et al. (2011) Blood 118 (19), 5292-5301; ; Sivaraman, B., et al. (2011) Biomaterials 32 (23), 5365-5370

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol

Immunology

NP_000165

P14770

Human

TKDCPSP CTCRALETMG LWVDCRGHGL TALPALPART RHLLLANNSL QSVPPGAFDH LPQLQTLDVT QNPWHCDCSL TYLRLWLEDR TPEALLQVRC ASPSLAAHGP LGRLTGYQLG SCGWQLQASW VRPG