Recombinant humaan GTF2H5 eiwit

GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

General transcription factor IIH subunit 5, General transcription factor IIH subunit 5, bA120J8.2, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

10.4 kDa (94aa) confirmed by MALDI-TOF

GTF2H5, General transcription factor IIH subunit 5, General transcription factor IIH subunit 5, bA120J8.2, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, ATGP2882-10 µg, ATGP2882-20 µg, ATGP2882-50 µg, ATGP2882-100 µg, ATGP2882-250 µg, ATGP2882-500 µg, ATGP2882-1 mg, ATGP2882-10, ATGP2882-20, ATGP2882-50, ATGP2882-100, ATGP2882-250, ATGP2882-500, ATGP2882-1

Giglia-Mari G., et al. (2004) Nat. Genet. 36:714-719

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Epigenomics (Transcription & Translation)

NP_997001

Q6ZYL4

Human

MVNVLKG VLIECDPAMK QFLLYLDESN ALGKKFIIQD IDDTHVFVIA ELVNVLQERV GELMDQNAFS LTQK