Recombinant humaan GTLF3B/NATD1-eiwit

Protein GTLF3B, also known as C17orf103, is a 113 amino acid protein that belongs to the GTLF3B family and is encoded by a gene that maps to human chromosome 17p11. 2. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. GTLF3B is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Recombinant human GTLF3B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein GTLF3B, Gtlf3b, C17orf103, N-acetyltransferase domain-containing protein 1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

15.4 kDa (136aa) confirmed by MALDI-TOF

Protein GTLF3B, GTLF3B, C17orf103, N-acetyltransferase domain-containing protein 1, N acetyltransferase domain-containing protein 1, ATGP2233-10 µg, ATGP2233-20 µg, ATGP2233-50 µg, ATGP2233-100 µg, ATGP2233-250 µg, ATGP2233-500 µg, ATGP2233-1 mg, ATGP2233-010, ATGP2233-020, ATGP2233-050, ATGP2233-100, ATGP2233-250, ATGP2233-500, ATGP2233-01M

Suela J., et al. (2007) J Clin Oncol. 25:1151-1152; ; Tai Y C., et al. (2007) J Natl Cancer Inset. 99:1811-1814.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Cancer

NP_690878

Q8N6N6

Human

MGSSHHHHHH SSGLVPRGSH MGSMAHSAAA VPLGALEQGC PIRVEHDRRR RQFTVRLNGC HDRAVLLYEY VGKRIVDLQH TEVPDAYRGR GIAKHLAKAA LDFVVEEDLK AHLTCWYIQK YVKENPLPQY LERLQP