Recombinant humaan haptoglobine/HP-eiwit

HP, as known as haptoglobin, is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its oxidative activity. The haptoglobin-hemoglobin complex will then be removed by the reticuloendothelial system (mostly the spleen) . Recombinant human HP protein, fused to His-tag at N-terminus, was expressed in E. coli

Haptoglobin isoform 2 preproprotein, Zonulin, BP, HP2ALPHA2, HPA1S

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

39.0 kDa (352aa)

HP, Haptoglobin isoform 2 preproprotein, Haptoglobin isoform 2 preproprotein, BP, HP2ALPHA2, HPA1S, ATGP2597-10 µg, ATGP2597-20 µg, ATGP2597-50 µg, ATGP2597-100 µg, ATGP2597-250 µg, ATGP2597-500 µg, ATGP2597-1 mg, ATGP2597-10, ATGP2597-20, ATGP2597-50, ATGP2597-100, ATGP2597-250, ATGP2597-500, ATGP2597-1

Dobryszycka W. et al. (1997) Eur J Clin Chem Clin Biochem. 35:647-654.; ; Wassell J. et al. (2000) Clin. Lab. 46:547-552.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Cardiovascular

NP_001119574.1

P00738

Human

VDSGNDV TDIADDGCPK PPEIAHGYVE HSVRYQCKNY YKLRTEGDGV YTLNNEKQWI NKAVGDKLPE CEAVCGKPKN PANPVQRILG GHLDAKGSFP WQAKMVSHHN LTTGATLINE QWLLTTAKNL FLNHSENATA KDIAPTLTLY VGKKQLVEIE KVVLHPNYSQ VDIGLIKLKQ KVSVNERVMP ICLPSKDYAE VGRVGYVSGW GRNANFKFTD HLKYVMLPVA DQDQCIRHYE GSTVPEKKTP KSPVGVQPIL NEHTFCAGMS KYQEDTCYGD AGSAFAVHDL EEDTWYATGI LSFDKSCAVA EYGVYVKVTS IQDWVQKTIA EN