Recombinant humaan HDDC2-eiwit

HDDC2 (HD domain-containing protein 2), also known as hepatitis C virus NS5A-transactivated protein 2, is an enzyme that contains one HD domain and belongs to the HDDC2 family. It is predicted to exhibit phosphohydrolase activity. This protein is suggested to participate in nucleic acid metabolism, signal transduction and possibly other functions in bacteria, archaea and eukaryotes. The HD domain consists of highly conserved residues, specifically histidines or aspartates. Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome have all been associated with this protein. Recombinant human HDDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

HD domain-containing protein 2, HD domain-containing protein 2, C6orf74, CGI-130, dJ167O5.2, NS5ATP2

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

25.8 kDa (227aa) confirmed by MALDI-TOF

HDDC2, HD domain-containing protein 2, HD domain-containing protein 2, C6orf74, CGI-130, dJ167O5.2, NS5ATP2, ATGP2896-10 µg, ATGP2896-20 µg, ATGP2896-50 µg, ATGP2896-100 µg, ATGP2896-250 µg, ATGP2896-500 µg, ATGP2896-1 mg, ATGP2896-10, ATGP2896-20, ATGP2896-50, ATGP2896-100, ATGP2896-250, ATGP2896-500, ATGP2896-1

Brunner, H.G. et al. (1994) Hum. Mol. Genet. 3:1561-1564.; ; Aravind, L. et al. (1998) Trends Biochem. Sci. 23:469-472.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Other

NP_057147

Q7Z4H3

Human

MASVSSA TFSGHGARSL LQFLRLVGQL KRVPRTGWVY RNVQRPESVS DHMYRMAVMA MVIKDDRLNK DRCVRLALVH DMAECIVGDI APADNIPKEE KHRREEEAMK QITQLLPEDL RKELYELWEE YETQSSAEAK FVKQLDQCEM ILQASEYEDL EHKPGRLQDF YDSTAGKFNH PEIVQLVSEL EAERSTNIAA AASEPHS