Recombinant humaan hematopoëtisch Prostaglandine D Synthase/HPGDS-eiwit

HPGDS, also known as GSTS, is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Recombinant human HPGDS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Hematopoietic prostaglandin D synthase, GSTS, PGDS, H-PGDS, PGD2, GSTS1-1, GSTS1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

25.9 kDa (223aa) confirmed by MALDI-TOF

Hematopoietic prostaglandin D synthase, GSTS, PGDS, H-PGDS, PGD2, GSTS1-1, GSTS1, HPGDS, H PGDS, ATGP1557-10 µg, ATGP1557-20 µg, ATGP1557-50 µg, ATGP1557-100 µg, ATGP1557-250 µg, ATGP1557-500 µg, ATGP1557-1 mg, ATGP1557-010, ATGP1557-020, ATGP1557-050, ATGP1557-100, ATGP1557-250, ATGP1557-500, ATGP1557-01M

Welter, H., et al. (2011) Fertil. Steril. 96 (2), 309-313; ; uchida, Y, et al. (2010) J. Inorg. Biochem. 104 (3), 331-340

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl,1mM DTT

Signal Transduction

NP_055300

O60760

Human

MPNYKL TYFNMRGRAE IIRYIFAYLD IQYEDHRIEQ ADWPEIKSTL PFGKIPILEV DGLTLHQSLA IARYLTKNTD LAGNTEMEQC HVDAIVDTLD DFMSCFPWAE KKQDVKEQMF NELLTYNAPH LMQDLDTYLG GREWLIGNSV TWADFYWEIC STTLLVFKPD LLDNHPRLVT LRKKVQAIPA VANWIKRRPQ TKL