Recombinant humaan HHEX-eiwit

HHEX is a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. HHEX has been shown to interact with Promyelocytic leukemia protein. Recombinant human HHEX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Hematopoietically-expressed homeobox protein HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

32.4 kDa (293aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

HHEX, Hematopoietically-expressed homeobox protein HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX, ATGP2239-10 µg, ATGP2239-20 µg, ATGP2239-50 µg, ATGP2239-100 µg, ATGP2239-250 µg, ATGP2239-500 µg, ATGP2239-1 mg, ATGP2239-10, ATGP2239-20, ATGP2239-50, ATGP2239-100, ATGP2239-250, ATGP2239-500, ATGP2239-1

Topcu Z, Mack DL, et al. (1999) . Oncogene. 18 (50) :7091-100.; ; Minami T, Murakami T, et al. (2004) . J Biol Chem. 279 (20) :20626-35.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% glycerol, 1mM DTT

Development

NP_002720

Q03014

Human

MQYPHPG PAAGAVGVPL YAPTPLLQPA HPTPFYIEDI LGRGPAAPTP APTLPSPNSS FTSLVSPYRT PVYEPTPIHP AFSHHSAAAL AAAYGPGGFG GPLYPFPRTV NDYTHALLRH DPLGKPLLWS PFLQRPLHKR KGGQVRFSND QTIELEKKFE TQKYLSPPER KRLAKMLQLS ERQVKTWFQN RRAKWRRLKQ ENPQSNKKEE LESLDSSCDQ RQDLPSEQNK GASLDSSQCS PSPASQEDLE SEISEDSDQE VDIEGDKSYF NAG