Recombinant humaan Histone Deacetylase 2/HDAC2-eiwit

HDAC2 belongs to the histone deacetylase family that act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones. It forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. It also plays an important role in transcriptional regulation, cell cycle progression and developmental events. Recombinant human HDAC2 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques.

Histone deacetylase 2, HD2, RPD3, YAF1, KDAC2, Protein deacylase HDAC2

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

56.4 kDa (496aa)

Histone Deacetylase2, HDAC2, Histone deacetylase 2, HD2, RPD3, YAF1, ATGP1154-10 µg, ATGP1154-20 µg, ATGP1154-50 µg, ATGP1154-100 µg, ATGP1154-250 µg, ATGP1154-500 µg, ATGP1154-1 mg, ATGP1154-10, ATGP1154-20, ATGP1154-50, ATGP1154-100, ATGP1154-250, ATGP1154-500, ATGP1154-1

Betz R. et al. (1998) Genomics. 52:245-6.; ; Taunton J. et al. (1996) Science 272:408-11

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF

Cell Cycle

NP_001518.3

Q92769

Human