Recombinant humaan HMGCS1-eiwit

HMGCS1 also known as hydroxymethylglutaryl-CoA synthase, cytoplasmic. This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Recombinant human HMGCS1 was expressed in E. coli and purified by using conventional chromatography techniques

Hydroxymethylglutaryl-CoA synthase cytoplasmic, Hydroxymethylglutaryl-CoA synthase, cytoplasmic, HMGCS

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

59.7 kDa (543aa)

HMGCS1, Hydroxymethylglutaryl-CoA synthase cytoplasmic, Hydroxymethylglutaryl-CoA synthase, cytoplasmic, HMGCS, ATGP3079-10 µg, ATGP3079-20 µg, ATGP3079-50 µg, ATGP3079-100 µg, ATGP3079-250 µg, ATGP3079-500 µg, ATGP3079-1 mg, ATGP3079-10, ATGP3079-20, ATGP3079-50, ATGP3079-100, ATGP3079-250, ATGP3079-500, ATGP3079-1

Rigbolt K.T., et al. (2011) Sci. Signal. 4:RS3-RS3.; ; Burkard T.R., et al. (2011) BMC Syst. Biol. 5:17-17.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Cardiovascular

NP_001091742

Q01581

Human

MGSSHHHHHH SSGLVPRGSH MGSMPGSLPL NAEACWPKDV GIVALEIYFP SQYVDQAELE KYDGVDAGKY TIGLGQAKMG FCTDREDINS LCMTVVQNLM ERNNLSYDCI GRLEVGTETI IDKSKSVKTN LMQLFEESGN TDIEGIDTTN ACYGGTAAVF NAVNWIESSS WDGRYALVVA GDIAVYATGN ARPTGGVGAV ALLIGPNAPL IFERGLRGTH MQHAYDFYKP DMLSEYPIVD GKLSIQCYLS ALDRCYSVYC KKIHAQWQKE GNDKDFTLND FGFMIFHSPY CKLVQKSLAR MLLNDFLNDQ NRDKNSIYSG LEAFGDVKLE DTYFDRDVEK AFMKASSELF SQKTKASLLV SNQNGNMYTS SVYGSLASVL AQYSPQQLAG KRIGVFSYGS GLAATLYSLK VTQDATPGSA LDKITASLCD LKSRLDSRTG VAPDVFAENM KLREDTHHLV NYIPQGSIDS LFEGTWYLVR VDEKHRRTYA RRPTPNDDTL DEGVGLVHSN IATEHIPSPA KKVPRLPATA AEPEAAVISN GEH