Recombinant humaan HNRNPA1-eiwit

HNRNPA1, also known as heterogeneous nuclear ribonucleoprotein A1, involved in the packaging of pre-mRNA into hnRNP particles, transport of poly (A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. This protein may play a role in HCV RNA replication. Recombinant human HNRNPA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, hnRNP-A1, HNRPA1, HNRPA1L3

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

36.6 kDa (343aa) confirmed by MALDI-TOF

HNRNPA1, Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, hnRNP-A1, HNRPA1, HNRPA1L3, ATGP1411-10 µg, ATGP1411-20 µg, ATGP1411-50 µg, ATGP1411-100 µg, ATGP1411-250 µg, ATGP1411-500 µg, ATGP1411-1 mg, ATGP1411-10, ATGP1411-20, ATGP1411-50, ATGP1411-100, ATGP1411-250, ATGP1411-500, ATGP1411-1

Kim C.S., et al. (2007) J. Virol. 81:3852-3865; ; Biamonti G., et al. (1989) J. Mol. Biol. 207:491-503

Nishikawa T, et al. HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells. (Sci Rep. 2019) {https://pubmed.ncbi.nlm.nih.gov/31311954/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT

Signal Transduction

NP_002127.1

P09651

Human

MSKSESP KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTDCVVMR DPNTKRSRGF GFVTYATVEE VDAAMNARPH KVDGRVVEPK RAVSREDSQR PGAHLTVKKI FVGGIKEDTE EHHLRDYFEQ YGKIEVIEIM TDRGSGKKRG FAFVTFDDHD SVDKIVIQKY HTVNGHNCEV RKALSKQEMA SASSSQRGRS GSGNFGGGRG GGFGGNDNFG RGGNFSGRGG FGGSRGGGGY GGSGDGYNGF GNDGSNFGGG GSYNDFGNYN NQSSNFGPMK GGNFGGRSSG PYGGGGQYFA KPRNQGGYGG SSSSSSYGSG RRF