Recombinant humaan HO-2/HMOX2-eiwit

HMOX2 is microsomal enzyme that cleave heme ring at the alpha methane bridge to produce the antioxidant biliverdin, inorganic iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin by bilibverdin reductase. This protein appears to be constitutively expressed in mammalian tissues. HMOX2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter. Recombinant HMOX2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Heme oxygenase 2, Heme oxygenase 2 Heme oxygenase (decycling) 2, Heme oxygenase (decyclizing) 2, HMOX 2, HMOX2 protein, HO 2, HO2

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

30.5 kDa (264aa) confirmed by MALDI-TOF

HO2, HMOX2, Heme oxygenase 2, Heme oxygenase 2 Heme oxygenase (decycling) 2, Heme oxygenase (decyclizing) 2, HMOX 2, HMOX2 protein, HO 2, HO2, ATGP0470-10 µg, ATGP0470-20 µg, ATGP0470-50 µg, ATGP0470-100 µg, ATGP0470-250 µg, ATGP0470-500 µg, ATGP0470-1 mg, ATGP0470-10, ATGP0470-20, ATGP0470-50, ATGP0470-100, ATGP0470-250, ATGP0470-500, ATGP0470-1

Baranano DE., et al. (2001) Proc Natl Acad Sci u S A. 98 (20) :10996-1002. ; ; Dore S., et al. (2002) Free Radic Biol Med. 32 (12) :1276-82.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Redox Proteins

NP_002125.3

P30519

Human

MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK