Recombinant humaan HOXA9-eiwit

HOXA9 belongs to the Abd-B homeobox family. This protein is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. Recombinant human HOXA9 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Homeobox protein Hox-A9, ABD-B, HOX1, HOX1.7, HOX1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

32.6 kDa (295aa)

HOXA9, Homeobox protein Hox-A9, ABD-B, HOX1, HOX1.7, HOX1, ATGP2667-10 µg, ATGP2667-20 µg, ATGP2667-50 µg, ATGP2667-100 µg, ATGP2667-250 µg, ATGP2667-500 µg, ATGP2667-1 mg, ATGP2667-10, ATGP2667-20, ATGP2667-50, ATGP2667-100, ATGP2667-250, ATGP2667-500, ATGP2667-1

Bandyopadhyay S., et al. (2012) Mol. Cell. Biol. 32:1202-1213; ; Patel C.V., et al. (1999) J. Biol. Chem. 274:1415-1422;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Stem Cell

NP_689952

P31269

Human

MGSSHHHHHH SSGLVPRGSH MGSMATTGAL GNYYVDSFLL GADAADELSV GRYAPGTLGQ PPRQAATLAE HPDFSPCSFQ SKATVFGASW NPVHAAGANA VPAAVYHHHH HHPYVHPQAP VAAAAPDGRY MRSWLEPTPG ALSFAGLPSS RPYGIKPEPL SARRGDCPTL DTHTLSLTDY ACGSPPVDRE KQPSEGAFSE NNAENESGGD KPPIDPNNPA ANWLHARSTR KKRCPYTKHQ TLELEKEFLF NMYLTRDRRY EVARLLNLTE RQVKIWFQNR RMKMKKINKD RAKDE