Recombinant humaan HOXC11-eiwit

HOXC11 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. Recombinant human HOXC11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Homeobox protein Hox-C11, HOX3H

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

36.1 kDa (327aa)

HOXC11, homeobox protein Hox-C11, HOX3H, ATGP2272-10 µg, ATGP2272-20 µg, ATGP2272-50 µg, ATGP2272-100 µg, ATGP2272-250 µg, ATGP2272-500 µg, ATGP2272-1 mg, ATGP2272-10, ATGP2272-20, ATGP2272-50, ATGP2272-100, ATGP2272-250, ATGP2272-500, ATGP2272-1

McIlroy, M., et al. (2010) Cancer Res. 70 (4), 1585-1594; ; Zhang, X., et al. (2007) J. Cell. Mol. Med. 11 (2), 299-306

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Epigenomics (Transcription & Translation)

NP_055027

O43248

Human

MFNSVNL GNFCSPSRKE RGADFGERGS CASNLYLPSC TYYMPEFSTV SSFLPQAPSR QISYPYSAQV PPVREVSYGL EPSGKWHHRN SYSSCYAAAD ELMHRECLPP STVTEILMKN EGSYGGHHHP SAPHATPAGF YSSVNKNSVL PQAFDRFFDN AYCGGGDPPA EPPCSGKGEA KGEPEAPPAS GLASRAEAGA EAEAEEENTN PSSSGSAHSV AKEPAKGAAP NAPRTRKKRC PYSKFQIREL EREFFFNVYI NKEKRLQLSR MLNLTDRQVK IWFQNRRMKE KKLSRDRLQY FSGNPLL