Recombinant humaan HPR-eiwit

HPR, also known as Haptoglobin-related protein, is a primate-specific plasma protein associated with apolipoprotein L-I (apoL-I) -containing high-density lipoprotein (HDL) particles shown to be a part of the innate immune defense. HPR-bound hemoglobin might contribute to the biologic activity of the circulating apoL-I/Hpr-containing HDL particles. Recombinant human HPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Haptoglobin-related protein, A-259H10.2, HP

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

39.3 kDa (352aa) confirmed by MALDI-TOF

HPR, Haptoglobin-related protein, A-259H10.2, HP, ATGP2581-10 µg, ATGP2581-20 µg, ATGP2581-50 µg, ATGP2581-100 µg, ATGP2581-250 µg, ATGP2581-500 µg, ATGP2581-1 mg, ATGP2581-10, ATGP2581-20, ATGP2581-50, ATGP2581-100, ATGP2581-250, ATGP2581-500, ATGP2581-1

Nielsen MJ. et al. (2008) Blood. 108:2846-2849.; ; Imrie HJ. et al. (2012) PLoS One. 7:e49816;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH8.5) containing 20% glycerol, 1mM DTT, 0.15M NaCl

Cancer

NP_066275

P00739

Human

LYSGNDV TDISDDRFPK PPEIANGYVE HLFRYQCKNY YRLRTEGDGV YTLNDKKQWI NKAVGDKLPE CEAVCGKPKN PANPVQRILG GHLDAKGSFP WQAKMVSHHN LTTGATLINE QWLLTTAKNL FLNHSENATA KDIAPTLTLY VGKKQLVEIE KVVLHPNYHQ VDIGLIKLKQ KVLVNERVMP ICLPSKNYAE VGRVGYVSGW GQSDNFKLTD HLKYVMLPVA DQYDCITHYE GSTCPKWKAP KSPVGVQPIL NEHTFCVGMS KYQEDTCYGD AGSAFAVHDL EEDTWYAAGI LSFDKSCAVA EYGVYVKVTS IQHWVQKTIA EN