Recombinant humaan HSFY1-eiwit

HSFY1 is a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human HSFY1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Heat shock transcription factor Y-linked isoform 1, Heat shock transcription factor, Y-linked isoform 1, Heat shock transcription factor, Y-linked 1, HSF2L, HSFY

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

47.5 kDa (424aa)

HSFY1, Heat shock transcription factor Y-linked isoform 1, Heat shock transcription factor, Y-linked isoform 1, Heat shock transcription factor, Y-linked 1, HSF2L, HSFY, ATGP2475-10 µg, ATGP2475-20 µg, ATGP2475-50 µg, ATGP2475-100 µg, ATGP2475-250 µg, ATGP2475-500 µg, ATGP2475-1 mg, ATGP2475-10, ATGP2475-20, ATGP2475-50, ATGP2475-100, ATGP2475-250, ATGP2475-500, ATGP2475-1

Skaletsky H., Kuroda-Kawaguchi T. et al. (2003) . Nature 423:825-837

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Signal Transduction

NP_149099

Q96LI6

Human

MGSSHHHHHH SSGLVPRGSH MGSMAHVSSE TQDVSPKDEL TASEASTRSP LCEHTFPGDS DLRSMIEEHA FQVLSQGSLL ESPSYTVCVS EPDKDDDFLS LNFPRKLWKI VESDQFKSIS WDENGTCIVI NEELFKKEIL ETKAPYRIFQ TDAIKSFVRQ LNLYGFSKIQ QNFQRSAFLA TFLSEEKESS VLSKLKFYYN PNFKRGYPQL LVRVKRRIGV KNASPISTLF NEDFNKKHFR AGANMENHNS ALAAEASEES LFSASKNLNM PLTRESSVRQ IIANSSVPIR SGFPPPSPST SVGPSEQIAT DQHAILNQLT TIHMHSHSTY MQARGHIVNF ITTTTSQYHI ISPLQNGYFG LTVEPSAVPT RYPLVSVNEA PYRNMLPAGN PWLQMPTIAD RSAAPHSRLA LQPSPLDKYH PNYN