Recombinant humaan HSPA8/HSC71-eiwit

HSC70, also known as heat shock 70 kDa protein 8, belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This protein is a heat-shock cognate protein. HSC70 binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Recombinant HSC70 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Heat shock 70 kDa protein 8, HSPA8, HSC54, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71, Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC70

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

73.1 kDa (666aa)

HSPA8, HSC71, Heat shock 70 kDa protein 8, HSPA8, HSC54, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71, Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC70, ATGP0415-10 µg, ATGP0415-20 µg, ATGP0415-50 µg, ATGP0415-100 µg, ATGP0415-250 µg, ATGP0415-500 µg, ATGP0415-1 mg, ATGP0415-10, ATGP0415-20, ATGP0415-50, ATGP0415-100, ATGP0415-250, ATGP0415-500, ATGP0415-1

Tsukahara F., et al. (2000) Mol Pharmacol. 58 (6) :1257-63. ; ; Dworniczak B., et al. (1987) Nucleic Acides Res. 15 (13) :5181-97.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Heat Shock Proteins

NP_006588.1

P11142

Human

MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA MNPTNTVFDA KRLIGRRFDD AVVQSDMKHW PFMVVNDAGR PKVQVEYKGE TKSFYPEEVS SMVLTKMKEI AEAYLGKTVT NAVVTVPAYF NDSQRQATKD AGTIAGLNVL RIINEPTAAA IAYGLDKKVG AERNVLIFDL GGGTFDVSIL TIEDGIFEVK STAGDTHLGG EDFDNRMVNH FIAEFKRKHK KDISENKRAV RRLRTACERA KRTLSSSTQA SIEIDSLYEG IDFYTSITRA RFEELNADLF RGTLDPVEKA LRDAKLDKSQ IHDIVLVGGS TRIPKIQKLL QDFFNGKELN KSINPDEAVA YGAAVQAAIL SGDKSENVQD LLLLDVTPLS LGIETAGGVM TVLIKRNTTI PTKQTQTFTT YSDNQPGVLI QVYEGERAMT KDNNLLGKFE LTGIPPAPRG VPQIEVTFDI DANGILNVSA VDKSTGKENK ITITNDKGRL SKEDIERMVQ EAEKYKAEDE KQRDKVSSKN SLESYAFNMK ATVEDEKLQG KINDEDKQKI LDKCNEIINW LDKNQTAEKE EFEHQQKELE KVCNPIITKL YQSAGGMPGG MPGGFPGGGA PPSGGASSGP TIEEVD