Recombinant humaan HVEM/TNFRSF14-eiwit

TNFRSF14, as known as tumor necrosis factor receptor superfamily member 14 isoform 1, is a type 1 membrane protein belonging to the TNF/NGF receptor superfamily. Expression of this protein has been detected in peripheral blood T cells, B cells, monocytes and in various tissue enriched in lymphoid cells. Binding of herpes simplex virus (HSV) viral envelope glycoprotein D to this receptor protein has been shown to be part of HSV entry mechanism, and from which its name derived. Recombinant human TNFRSF14, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2, CD270, HVEM, ATAR, LIGHTR

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

44.6 kDa (406aa)

HVEM, TNFRSF14, Tumor necrosis factor receptor superfamily member 14 isoform 1, TNFRSF14, ATAR, CD270, HVEA, HVEM, LIGHTR, TR2, HVEML, CD40 like protein precursor, Herpes virus entry mediator A, Herpesvirus entry mediatorHerpesvirus entry mediator A, Herpesvirus entry mediator ligand, HveA, HVEM L, LIGHT, LIGHTRTNFRSF14, TNFSF 14, TNR14_HUMANTR2, Tumor necrosis factor receptor like gene2Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor superfamily member 14 precursor, Tumor necrosis factor receptor-like 2, ATGP3379-10 µg, ATGP3379-20 µg, ATGP3379-50 µg, ATGP3379-100 µg, ATGP3379-250 µg, ATGP3379-500 µg, ATGP3379-1 mg, ATGP3379-10, ATGP3379-20, ATGP3379-50, ATGP3379-100, ATGP3379-250, ATGP3379-500, ATGP3379-1

Inoue T., et al. (2015) Anticancer Res. 35:1361-1367.; ; Steinberg MW., et al. (2011) Immunol. Rev. 244:169-187.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_003811

Q92956

Human

Ala

LPSCKED EYPVGSECCP KCSPGYRVKE ACGELTGTVC EPCPPGTYIA HLNGLSKCLQ CQMCDPAMGL RASRNCSRTE NAVCGCSPGH FCIVQDGDHC AACRAYATSS PGQRVQKGGT ESQDTLCQNC PPGTFSPNGT LEECQHQTKC SWLVTKAGAG TSSSHWV