Recombinant humaan IFN-alfa 7/IFNA7 eiwit

IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant human IFNA7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interferon alpha-7, IFNA7, IFN-alphaJ, IFNA-J, Interferon alpha-J1, IFN-alpha-J1

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

20.7 kDa (175aa)

IFNA7, Interferon alpha-7, IFNA7, IFN-alphaJ, IFNA-J, ATGP3810-10 µg, ATGP3810-20 µg, ATGP3810-50 µg, ATGP3810-100 µg, ATGP3810-250 µg, ATGP3810-500 µg, ATGP3810-1 mg, ATGP3810-10, ATGP3810-20, ATGP3810-50, ATGP3810-100, ATGP3810-250, ATGP3810-500, ATGP3810-1

De Veer MJ., et al. (2001) J Leukoc Biol. 69:912-920.; ; Fensterl V., et al. (2009) Biofactors. 35:14-20.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_066401

P01567

Human

Ala

CDLPQTH SLRNRRALIL LAQMGRISPF SCLKDRHEFR FPEEEFDGHQ FQKTQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDFI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSFSFSTN LKKGLRRKD