Recombinant humaan IGFBP-6 eiwit

IGFBP6 contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Recombinant human IGFPB6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Insulin-like growth factor-binding protein 6, IBP6

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

25 kDa (236aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

IGFBP6, Insulin-like growth factor-binding protein 6, IBP6, ATGP2270-10 µg, ATGP2270-20 µg, ATGP2270-50 µg, ATGP2270-100 µg, ATGP2270-250 µg, ATGP2270-500 µg, ATGP2270-1 mg, ATGP2270-10, ATGP2270-20, ATGP2270-50, ATGP2270-100, ATGP2270-250, ATGP2270-500, ATGP2270-1

Shimasaki S., et al (1991), Mol. Endocrinol. 5:938-948; ; Andress D.L., et al (1991), Biochem. Biophys. Res. Commun. 176:213-218 (1991)

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.5) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Hormones & Cytokines

NP_002169.1

P24592

Human

MGSSHHHHHH SSGLVPRGSH MGSRCPGCGQ GVQAGCPGGC VEEEDGGSPA EGCAEAEGCL RREGQECGVY TPNCAPGLQC HPPKDDEAPL RALLLGRGRC LPARAPAVAE ENPKESKPQA GTARPQDVNR RDQQRNPGTS TTPSQPNSAG VQDTEMGPCR RHLDSVLQQL QTEVYRGAQT LYVPNCDHRG FYRKRQCRSS QGQRRGPCWC VDRMGKSLPG SPDGNGSSSC PTGSSG