Recombinant humaan IL-10R beta/IL10RB eiwit

IL10RB, also known as interleukin-10 receptor subunit beta, is a transmembrane glycoprotein that functions as a co-receptor for several class 2 cytokines including Interleukins-10, -22, -26, -28A/IFN-lambda 2, -28B/IFN-lambda 3, and -29/IFN-lambda. Co-expression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Recombinant human IL10RB protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2, CDw210b, CRFB4, D21S58, D21S66

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

50.5 kDa (440aa)

IL10 R b, Interleukin-10 receptor subunit beta, IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, ATGP3664-10 µg, ATGP3664-20 µg, ATGP3664-50 µg, ATGP3664-100 µg, ATGP3664-250 µg, ATGP3664-500 µg, ATGP3664-1 mg, ATGP3664-10, ATGP3664-20, ATGP3664-50, ATGP3664-100, ATGP3664-250, ATGP3664-500, ATGP3664-1

Khare V., et al, (2015) Cancer Immunol Res. 3:1227-1235.; ; Spencer SD., et al, (1998) J. Exp. Med. 187: 571-578.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000619

Q08334

Human

Met20