Recombinant humaan IL-13R alfa 2/IL13RA2-eiwit

IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. Recombinant human IL13RA2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Interleukin 13 receptor subunit alpha 2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL13R, IL13BP, cancer/testis antigen 19, CT19

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

39.5 kDa (340aa)

IL13 R a2, interleukin-13 receptor subunit alpha-2 precursor, CD213A2, CT19, IL-13R, IL13BP, ATGP2139-10 µg, ATGP2139-20 µg, ATGP2139-50 µg, ATGP2139-100 µg, ATGP2139-250 µg, ATGP2139-500 µg, ATGP2139-1 mg, ATGP2139-10, ATGP2139-20, ATGP2139-50, ATGP2139-100, ATGP2139-250, ATGP2139-500, ATGP2139-1

Fujisawa, T., et al. (2012) Int. J. Cancer 131 (2), 344-356; ; Barderas, R., et al. (2012) Cancer Res. 72 (11), 2780-2790

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Immunology

NP_000631

Q14627

Human

DTEIKVN PPQDFEIVDP GYLGYLYLQW QPPLSLDHFK ECTVEYELKY RNIGSETWKT IITKNLHYKD GFDLNKGIEA KIHTLLPWQC TNGSEVQSSW AETTYWISPQ GIPETKVQDM DCVYYNWQYL LCSWKPGIGV LLDTNYNLFY WYEGLDHALQ CVDYIKADGQ NIGCRFPYLE ASDYKDFYIC VNGSSENKPI RSSYFTFQLQ NIVKPLPPVY LTFTRESSCE IKLKWSIPLG PIPARCFDYE IEIREDDTTL VTATVENETY TLKTTNETRQ LCFVVRSKVN IYCSDDGIWS EWSDKQCWEG EDLSKKTLLR