Recombinant humaan IL-17B-eiwit

IL17B, also known as interleukin-17B isoform 1, is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. It plays a role in inflammation and bone growth. IL-17B binds to IL-17 RB and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells. Recombinant human IL17B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, NIRF, ZCYTO7

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

19.2 kDa (169aa)

ZCYTO7, NIRF, Neuronal interleukin-17-related factor, Neuronal interleukin 17 related factor, Interleukin-20, Interleukin20, Interleukin 20, Interleukin-17B precursor, Interleukin-17B isoform 1, Interleukin 17B precursor, Interleukin 17B isoform 1, Interleukin17B, Interleukin-17B, Interleukin 17B, IL-20, IL 20, IL20, IL-17B, IL 17B, IL17B, Cytokine Zcyto7, ATGP3535-10 µg, ATGP3535-20 µg, ATGP3535-50 µg, ATGP3535-100 µg, ATGP3535-250 µg, ATGP3535-500 µg, ATGP3535-1 mg, ATGP3535-010, ATGP3535-020, ATGP3535-050, ATGP3535-100, ATGP3535-250, ATGP3535-500, ATGP3535-01M

Yamaguchi Y., et al. (2007) J Immunol. 179:7128-136; ; Reynolds JM., et al. (2015) Immunity. 42:692-703

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_055258

Q9UHF5

Human

Ala

QPRSPKS KRKGQGRPGP LAPGPHQVPL DLVSRMKPYA RMEEYERNIE EMVAQLRNSS ELAQRKCEVN LQLWMSNKRS LSPWGYSINH DPSRIPVDLP EARCLCLGCV NPFTMQEDRS MVSVPVFSQV PVRRRLCPPP PRTGPCRQRA VMETIAVGCT CIF