Recombinant humaan IL-17R alfa/IL17RA-eiwit

IL17RA, also known as interleukin-17 receptor A isoform 1, is a cytokine receptor which binds interleukin 17. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. It is a type1 membrane glycoprotein that binds with low affinity to interleukin 17A. This protein and Interleukin 17A play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Recombinant human IL17RA, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-17 receptor A isoform 1, IL17RA, CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R, IMD51, Macrophagleukin-17 receptor 2

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

60.4 kDa (527aa)

IL17 RA, IL17 R, Interleukin-17 receptor A isoform 1, IL17RA, CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R, IMD51, ATGP3632-10 µg, ATGP3632-20 µg, ATGP3632-50 µg, ATGP3632-100 µg, ATGP3632-250 µg, ATGP3632-500 µg, ATGP3632-1 mg, ATGP3632-10, ATGP3632-20, ATGP3632-50, ATGP3632-100, ATGP3632-250, ATGP3632-500, ATGP3632-1

Honorati MC., et al, (2001) Rheumatology 40:522-527.; ; Yao Z., et al, (1997) Cytokine 9:794-800.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_055154

Q96F46

Human

Leu33