Recombinant humaan IL-1R alfa/IL1R1-eiwit

IL1R1, also known as interleukin-1 receptor type 1, associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. It is an important mediator involved in many cytokine induced immune and inflammatory responses. Recombinant human IL1R1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-1 receptor type 1, Interleukin-1 receptor type I, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, p80, CD121a, IL-1R-1, IL-1RT-1, IL1R, IL1RA

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

37.4 kDa (324aa)

IL1 RI, IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, Interleukin 1 receptor type 1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, IL-1R-1, IL-1RT-1, IL-1RT1, IL1R, IL1RA, ATGP3213-10 µg, ATGP3213-20 µg, ATGP3213-50 µg, ATGP3213-100 µg, ATGP3213-250 µg, ATGP3213-500 µg, ATGP3213-1 mg, ATGP3213-010, ATGP3213-020, ATGP3213-050, ATGP3213-100, ATGP3213-250, ATGP3213-500, ATGP3213-01M

Beaulieu LM., et al. (2014) Arterioscler. Thromb. Vasc. Biol. 34: (3) 552-564.; ; Moos V., et al. (2000) Arthritis Rheum. 43 (11) :2417-22.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_000868.1

P14778

Human