Recombinant humaan IL-21R-eiwit

IL21R, also known as Interleukin-21 receptor, belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Recombinant human IL21R, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 21 receptor, IL-21 receptor, Novel interleukin receptor, NILR, CD360

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

25.6 kDa (221aa)

CD 360, CD360, IL-21R, IL-21 R, IL 21 R, IL21 R, IL-21 receptor, IL21R, Interleukin 21 receptor, Interleukin-21 receptor, Interleukin21 receptor, Interleukin 21 R, Interleukin-21 R, Interleukin21 R, NILR, Novel interleukin receptor, ATGP3182-10 µg, ATGP3182-20 µg, ATGP3182-50 µg, ATGP3182-100 µg, ATGP3182-250 µg, ATGP3182-500 µg, ATGP3182-1 mg, ATGP3182-010, ATGP3182-020, ATGP3182-050, ATGP3182-100, ATGP3182-250, ATGP3182-500, ATGP3182-01M

Parrish-Novak J. et al., (2000) Nature 408:57-63.; ; Hamming OJ. et al., (2012) J Biol Chem. 287 (12) :9454-60.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_851564

Q9HBE5

Human

CPDLVCYTDY LQTVICILEM WNLHPSTLTL TWQDQYEELK DEATSCSLHR SAHNATHATY TCHMDVFHFM ADDIFSVNIT DQSGNYSQEC GSFLLAESIK PAPPFNVTVT FSGQYNISWR SDYEDPAFYM LKGKLQYELQ YRNRGDPWAV SPRRKLISVD SRSVSLLPLE FRKDSSYELQ VRAGPMPGSS YQGTWSEWSD PVIFQTQSEE LKEVEHHHHH H