Recombinant humaan IL-23R-eiwit

IL23R, also known as interleukin-23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK and dendritic cells. It may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Recombinant human IL23R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin-23 receptor, IL-23R, IL-23 receptor

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

65.3 kDa (574aa)

Interleukin-23 receptor, Interleukin23 receptor, Interleukin 23 receptor, IL23R_HUMAN, IL-23R, IL23R, IL-23 receptor, IL23 receptor, IL-23 R, IL23 R, IL 23R, IL 23 receptor, ATGP3424-10 µg, ATGP3424-20 µg, ATGP3424-50 µg, ATGP3424-100 µg, ATGP3424-250 µg, ATGP3424-500 µg, ATGP3424-1 mg, ATGP3424-010, ATGP3424-020, ATGP3424-050, ATGP3424-100, ATGP3424-250, ATGP3424-500, ATGP3424-01M

Dubinsky MC., et al. (2007) Inflamm Bowel Dis. 13:511-515.; ; Yao J., et al. (2014) Gene. 533:21-25.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_653302.2

Q5VWK5

Human

Ala

GITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIG