Recombinant humaan IL-28A/IFNL2-eiwit

IFNL2, also known as Interleukin 28A (IL28A), is a cytokine distantly related to type I interferons and the IL-10 family. Interleukin 28A (IL28A), Interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) . Recombinant human IFNL2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Interferon lambda 2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, ZCYTO20

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

22.1 kDa (198aa)

IL28A, IFN-lambda2, Interferon lambda-2, Interferon, lambda 2, IL-28A, IL28A, ATGP2563-10 µg, ATGP2563-20 µg, ATGP2563-50 µg, ATGP2563-100 µg, ATGP2563-250 µg, ATGP2563-500 µg, ATGP2563-1 mg, ATGP2563-10, ATGP2563-20, ATGP2563-50, ATGP2563-100, ATGP2563-250, ATGP2563-500, ATGP2563-1

Sheppard P., et al. (2003) Nat. Immunol. 4:63-68.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Hormones & Cytokines

NP_742150

Q8IZJ0

Human

MGSSHHHHHH SSGLVPRGSH MGSVPVARLH GALPDARGCH IAQFKSLSPQ ELQAFKRAKD ALEESLLLKD CRCHSRLFPR TWDLRQLQVR ERPMALEAEL ALTLKVLEAT ADTDPALVDV LDQPLHTLHH ILSQFRACIQ PQPTAGPRTR GRLHHWLYRL QEAPKKESPG CLEASVTFNL FRLLTRDLNC VASGDLCV