Recombinant humaan IL-28B/IFNL3-eiwit

IFNL3, also known as Interferon lambda-3, is a secreted protein which belongs to the IL-28/IL-29 family. It is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. This protein displays potent antiviral activity and antitumor activity. It seems to signal through the Jak-STAT pathway. It also contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection. Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Cytokine Zcyto22, IL28B, IL-28B, IL28C, IL-28C, Interferon lambda-3, Interleukin-28B, Interleukin-28C, ZCYTO22

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

20.4 kDa (181aa)

Cytokine Zcyto22, IFNL3, IL 28 B, IL 28 C, IL 28B, IL 28C, IL28B, IL-28B, IL28C, IL-28C, Interferon lambda 3, Interferon lambda3, Interferon lambda-3, Interleukin 28B, Interleukin 28C, Interleukin28B, Interleukin-28B, Interleukin28C, Interleukin-28C, ZCYTO22, ATGP3080-10 µg, ATGP3080-20 µg, ATGP3080-50 µg, ATGP3080-100 µg, ATGP3080-250 µg, ATGP3080-500 µg, ATGP3080-1 mg, ATGP3080-010, ATGP3080-020, ATGP3080-050, ATGP3080-100, ATGP3080-250, ATGP3080-500, ATGP3080-01M

Kamal SM. et al. (2014) Am J Gastroenterol. 109 (2) :199-211.; ; Frizon K. et al. (2014) Braz J Infect Dis. 18 (2) :229-30.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM EDTA, 0.1mM PMSF.

Hormones & Cytokines

NP_742151.2

Q8IZI9

Human