Recombinant humaan IL-2R alfa/IL2RA-eiwit

IL2RA, also known as interleukin-2 receptor subunit alpha isoform 1, is a type 1 transmembrane glycoprotein. This protein is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, mastocytosis and tumor infiltrating lymphocytes. It functions as the receptor for HTLV-1 and is consequently expressed on neoplastic cells in adult T cell lymphoma/leukemia. Also, it is elevated in proliferative disturbances of the hematopoietic system and in many solid tumors. Recombinant human IL2RA, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 2 receptor subunit alpha, Insulin-dependent diabetes mellitus 10, Interleukin 2 receptor alpha, IL2R, IDDM10, CD25, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

52.1 kDa (461aa)

CD25, IL2 R a, Interleukin-2 receptor subunit alpha isoform 1, IL2RA, CD25, IDDM10, IL2R, IMD41, p55, TCGFR, ATGP3616-10 µg, ATGP3616-20 µg, ATGP3616-50 µg, ATGP3616-100 µg, ATGP3616-250 µg, ATGP3616-500 µg, ATGP3616-1 mg, ATGP3616-10, ATGP3616-20, ATGP3616-50, ATGP3616-100, ATGP3616-250, ATGP3616-500, ATGP3616-1

Kuziel WA., et al, (1990) J. Invest. Dermatol. 94:27S-32S.; ; Purvis SF., et al, (1992) Cell. Immunol. 144:32-42.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000408

P01589

Human

Ala

ADPELCDDDP PEIPHATFKA MAYKEGTMLN CECKRGFRRI KSGSLYMLCT GNSSHSSWDN QCQCTSSATR NTTKQVTPQP EEQKERKTTE MQSPMQPVDQ ASLPGHCREP PPWENEATER IYHFVVGQMV YYQCVQGYRA LHRGPAESVC KMTHGKTRWT QPQLICTGEM ETSQFPGEEK PQASPEGRPE SETSCLVTTT DFQIQTEMAA TMETSIFTTE YQLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H